Learn the most recent CPR guidelines in this article. These CPR guidelines represent the gold standard for cardiopulmonary resuscitation, encompassing evidence-based techniques and best practices to ensure effective and standardized CPR delivery. They are developed and regularly updated by esteemed organizations such as the American Heart Association (AHA) and the International Liaison Committee on Resuscitation (ILCOR). Their objective is to provide healthcare professionals, first responders, and the general public with the latest, scientifically supported information on CPR to enhance survival rates during cardiac emergencies.
Updated as of October 2025: The latest AHA and ILCOR CPR guideline updates introduce new recommendations and refinements based on the most recent research in resuscitation science. These updates focus on improving survival outcomes through enhanced systems of care, refined CPR techniques, integrated opioid response protocols, and a unified Chain of Survival applicable to all age groups.
Adult CPR Guidelines
Cardiopulmonary Resuscitation (CPR) is a critical life-saving skill that can be performed by anyone. The 2025 American Heart Association (AHA) Guidelines for CPR and Emergency Cardiovascular Care (ECC) include the following major updates for adult resuscitation:
Unified Chain of Survival
A single Chain of Survival now applies to all cardiac arrests in adults, children, and newborns, whether in-hospital or out-of-hospital. The links remain early recognition and activation, high-quality CPR, rapid defibrillation, advanced life support, and post-arrest care.
High-quality CPR refinements
- Perform compressions on a firm surface at a rate of 100–120 per minute with a depth of at least 2 inches (5 cm).
 - Minimize interruptions, keeping pauses under 10 seconds.
 - For trained professionals, during respiratory arrest with a pulse but no breathing, give one breath every 6 seconds (about 10 breaths per minute).
 - The routine use of mechanical CPR devices is not recommended unless manual compressions are not feasible.
 
Opioid-related emergency response
A new algorithm guides the management of suspected opioid overdose. Recognize signs such as slow or absent breathing, pinpoint pupils, and cyanosis. Administer naloxone if available and integrate CPR and defibrillation as needed.
Defibrillation and ALS updates
- For atrial fibrillation, an initial synchronized cardioversion energy of 200 J or higher is reasonable.
 - The benefit of double-sequential defibrillation in refractory VF or pulseless VT remains uncertain.
 - Vasopressin offers no advantage over epinephrine alone outside of clinical trials.
 - Temporary transvenous pacing is reasonable for adults with persistent, unstable bradycardia that does not respond to therapy.
 
Systems and ethics focus
The new ethics chapter highlights the principles of beneficence, non-maleficence, respect for autonomy, and justice. It emphasizes fairness and addressing health inequities. The AHA also stresses community education, bystander CPR training, and continuous quality improvement in resuscitation systems.
Pediatric CPR Guidelines
Pediatric CPR differs from adult CPR because infants and children have unique physiological needs. The 2025 American Heart Association (AHA) Guidelines for CPR and Emergency Cardiovascular Care (ECC) outline key updates and refinements to ensure effective pediatric resuscitation.
- The 2025 AHA Guidelines unify the Chain of Survival for all ages, including pediatric patients.
 - For children, perform compressions at least 2 inches (5 cm) deep or one-third of the chest diameter.
 - For infants, compress about 1.5 inches (4 cm) deep at a rate of 100–120 compressions per minute.
 - The 2-finger technique is no longer recommended; use the heel of one hand or the two-thumb encircling hands technique.
 - Maintain a 30:2 compression-to-ventilation ratio for single rescuers and 15:2 for two rescuers.
 - Minimize interruptions in compressions to less than 10 seconds.
 - Children aged 12 years and older can now be trained to perform CPR and use an AED.
 - Use feedback devices and video-assisted dispatch to improve CPR quality.
 - For newborns not requiring immediate resuscitation, delay cord clamping for at least 60 seconds (previously ~30 seconds).
 - Pediatric cardiac arrest survivors should receive physical, cognitive, and emotional evaluation within the first year after arrest.
 
What is CPR?
CPR, short for Cardiopulmonary Resuscitation, is a crucial life-saving technique that aims to sustain blood circulation and oxygenation in individuals experiencing cardiac arrest. During sudden cardiac arrest, the heart stops effectively pumping blood, and breathing ceases. CPR involves a combination of chest compressions and rescue breaths, if trained to do so, to maintain the flow of oxygen-rich blood to vital organs, particularly the brain, until professional medical help arrives.
Importance of the CPR Guidelines
- Evidence-Based Approach: The CPR guidelines are meticulously crafted based on the latest scientific research and clinical studies. They reflect evidence-driven insights and expert consensus, ensuring that the techniques recommended are rooted in proven effectiveness.
 - Consistency and Standardization: The guidelines promote uniformity in CPR practices, minimizing variations in techniques across different providers and settings. By following standardized protocols, responders works cohesively and optimize outcomes for patients.
 - Adaptation to Changing Knowledge: As medical knowledge advances, the CPR guidelines are continuously updated to incorporate new findings. This dynamic approach allows for the integration of cutting-edge discoveries into life-saving procedures.
 - Real-Time Relevance: Regular updates ensure that the guidelines remain relevant to the contemporary challenges and scenarios faced by healthcare professionals and lay rescuers alike. This adaptability ensures that CPR techniques align with current medical trends and technologies.
 - Training and Education: The guidelines serve as a cornerstone for CPR certifications and education programs. By adhering to the latest guidelines, instructors instills the most current and effective skills in CPR trainees.
 
Who Should Perform CPR?
Anyone is capable to perform CPR. Cardiopulmonary Resuscitationis a vital life-saving technique that is performed by anyone, regardless of their medical background or training. The earlier CPR is initiated, the better the chances of survival for the person in distress. Prompt action from a bystander significantly increase the likelihood of a positive outcome.
If you are untrained or unsure about performing rescue breaths, you can still help through hands-only CPR. This technique focuses solely on chest compressions and is an effective way to keep blood flowing to vital organs until professional help arrives.

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