Epinephrine Practice Test

Epinephrine is a life-saving medication used to treat severe allergic reactions, such as anaphylaxis. If you work in healthcare, education, or other occupations where you may need to administer epinephrine, it's crucial to have a thorough understanding of how to properly administer this medication. Our Epinephrine practice test is designed to help you prepare for real-life emergencies and covers all aspects of epinephrine administration, including recognizing anaphylaxis, selecting the appropriate dose and route of administration, and handling adverse reactions. By taking our Epinephrine practice test regularly, you can stay up-to-date with the latest protocols and techniques and receive detailed feedback to improve your knowledge of epinephrine administration.

This online quiz practice simulates real-life emergency situations, helping you review vital steps such as:

  • Recognizing signs and symptoms of anaphylaxis
  • Choosing the correct epinephrine dosage and administration route
  • Safely managing adverse reactions
  • Preparing for emergencies involving severe allergic reactions

Sample 20 Questions

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What is the first step you should take if a person is showing symptoms of anaphylaxis?

A. Make sure the person is sitting in a comfortable position.

B. Have the person lie down if they are showing signs of shock.

C. Call 911 or the designated emergency number immediately.

D. Give the victim medication to ease the allergic reaction


What is the most common symptom of anaphylaxis?

A. Itchy eyes

B. Swelling of the throat

C. Difficulty breathing

D. Nausea and vomiting


What is a common trigger of Anaphylaxis?

A. Foods like peanuts, fish, shellfish, fruit, milk, eggs, soy, and wheat

B. Environment

C. Medicine such as antibiotics, aspirin, and ibuprofen

D. A and C


If you are a nurse, what is the most critical step to prevent anaphylactic shock in a patient?

A. Establishing IV access

B. Administering Epinephrine

C. Administering Corticosteroids

D. Assessing, documenting, and avoiding all the patient allergies


A 20-year-old female is admitted to the ER due to a bee sting. According to the guardian, the patient is severely allergic to bees and was recently stung by one. What type of anaphylactic reaction is the patient experiencing?

A. Type I Hypersensitivity Reaction

B. Type II Hypersensitivity Reaction

C. Type III Hypersensitivity Reaction

D. Type IV Hypersensitivity Reaction


You’re educating a patient with a severe peanut allergy on how to recognize the signs and symptoms of anaphylactic shock. Which of the following signs and symptoms are associated with anaphylactic shock?

A. Hyperglycemia

B. Difficulty speaking

C. Hypertension

D. Slow heart rate

A patient has a sudden and severe anaphylactic reaction to a medication. You immediately stop the medication and call rapid response. The patient’s blood pressure is 80/52, heart rate 120, and oxygen saturation 87%. Audible wheezing is noted, along with facial redness and swelling. What should be the first initial treatment for this patient’s condition as a healthcare provider?

A. IV Diphenhydramine

B. IV Normal Saline Bolus

C. IM Epinephrine

D. Nebulized Albuterol

A severe peanut allergy patient mistakenly consumed an egg roll containing peanut ingredients during his lunch break. As a result, the patient is given Epinephrine intramuscularly. As the nurse, you know this medication will have what effect on the body?

A. It will prevent a recurrent attack.

B. It will cause vasoconstriction and decrease blood pressure.

C. It will help dilate the airways.

D. It will help block the effects of histamine in the body.

A patient is having an anaphylactic reaction to an IV medication. What is the FIRST action you should take?

A. Administer Epinephrine

B. Call a Rapid Reponse

C. Stop the medication

D. Administer a breathing treatment


What's the BEST way to manage Anaphylaxis if you are at risk?

A. Avoid allergens that trigger symptoms

B. Carry Epinephrine Auto-Injector

C. Know how to use Epinephrine

D. All of the above

Where should Epinephrine be injected?

A. Arms

B. Thigh

C. Buttocks

D. Neck

Which of the following is TRUE about Epinephrine?

A. Epinephrine should be given early in symptoms of anaphylaxis

B. Only people with mild allergies should carry epinephrine

C. It's not necessary to refill your prescription if your epinephrine has expired

D. People with a history of anaphylaxis are not allowed to use Epinephrine auto-injectors.

Which of the following statement is TRUE about Epinephrine auto-injectors

A. Auto-injectors are an approved 2nd-line of treatment for Anaphylaxis

B. You can buy Epinephrine auto-injectors without prescription

C. Auto-injectors work quickly to reverse the symptoms of an anaphylactic reaction.

D. Epinephrine Auto-injector doesn't belong to a class of drugs called Alpha/Beta-Adrenergic Agonists. 

What is the correct dose of Auvi-Q for a child who weighs 33 lbs?

A. Auvi-Q 0.1mg

B. Auvi-Q 0.15mg

C. Auvi-Q 0.3mg

D. Auvi-Q 0.4mg


You’re teaching a patient how to use their EpiPen in case of an anaphylactic reaction using an EpiPen trainer device. How will the patient demonstrate how to administer the medication? 

A. The patient injects the medication into the subq tissue of the abdomen.

B. The patient massages the site after injection.

C. The patient administers the injection through the clothes.

D. B and C

Ready to Get Certified?

After mastering the quiz, consider enrolling in our EpiPen Training Certification Course:

  • Learn how to recognize anaphylaxis and use autoinjectors correctly
  • Gain scenario-based practice in schools, clinics, and community settings
  • Understand maintenance, dose variations, and side effect management
  • Earn a printable certification valid for 1 year